• Gene id: 219995

Gene Summary

• Gene Symbol: MS4A15   Gene   UCSC   Ensembl
• Gene name: membrane spanning 4-domains A15
• Alternate names: membrane-spanning 4-domains subfamily A member 15,
• Gene location: 11q12.2 (60756866: 60776732)     Exons: 8     NC_000011.10

Protein Summary

• Protein general information: Q8N5U1  
  • Name: Membrane spanning 4 domains subfamily A member 15
  • Length: 240  
  • Mass: 25050
• Sequence:

  MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLG
  TVQILIGLIHLGFGSVLLMVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAA
  FAGTAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAAS
  APPAYDNVAYAQGVV

• Structural information:
  • Interpro: IPR007237  IPR030417  
  • STRING: ENSP00000386022
• Other Databases: GeneCards:  MS4A15  Malacards:  MS4A15

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray