• Gene id: 201895

Gene Summary

• Gene Symbol: SMIM14   Gene   UCSC   Ensembl
• Aliases: C4orf34
• Gene name: small integral membrane protein 14
• Alternate names: small integral membrane protein 14,
• Gene location: 4p14 (39638864: 39546335)     Exons: 7     NC_000004.12
• OMIM: 0

Protein Summary

• Protein general information: Q96QK8  
  • Name: Small integral membrane protein 14
  • Length: 99  
  • Mass: 10710
• Sequence:

  MAEGGFDPCECVCSHEHAMRRLINLLRQSQSYCTDTECLQELPGPSGDNGISVTMILVAWMVIALILFLLRPPNL
  RGSSLPGKPTSPHNGQDPPAPPVD

• Structural information:
  • Interpro: IPR020309  
  • STRING: ENSP00000295958
• Other Databases: GeneCards:  SMIM14  Malacards:  SMIM14

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005783	endoplasmic reticulum	IBA	cellular component
GO:0005783	endoplasmic reticulum	IDA	cellular component
GO:0005783	endoplasmic reticulum	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0001835	blastocyst hatching	IEA	biological process
GO:0005789	endoplasmic reticulum membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray