• Gene id: 200728

Gene Summary

• Gene Symbol: TMEM17   Gene   UCSC   Ensembl
• Gene name: transmembrane protein 17
• Alternate names: transmembrane protein 17,
• Gene location: 2p15 (62511893: 62452777)     Exons: 10     NC_000002.12
• OMIM: 614950

Protein Summary

• Protein general information: Q86X19  
  • Name: Transmembrane protein 17
  • Length: 198  
  • Mass: 23046
• Sequence:

  MELPDPVRQRLGNFSRAVFSDSNRTGPESNEGPENEMVSSLALQMSLYFNTYYFPLWWVSSIMMLHMKYSILPDY
  YKFIVITVIILITLIEAIRLYLGYVGNLQEKVPELAGFWLLSLLLQLPLILFLLFNEGLTNLPLEKAIHIIFTLF
  LAFQVVAAFLTLRKMVNQLAVRFHLQDFDRLSANRGDMRRMRSCIEEI

• Structural information:
  • Interpro: IPR019184  
  • STRING: ENSP00000335094
• Other Databases: GeneCards:  TMEM17  Malacards:  TMEM17

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0035869	ciliary transition zone	IBA	cellular component
GO:1905515	non-motile cilium assembly	IBA	biological process
GO:0030030	cell projection organization	IEA	biological process
GO:0042995	cell projection	IEA	cellular component
GO:0005886	plasma membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005929	cilium	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:1905515	non-motile cilium assembly	IMP	biological process
GO:0060170	ciliary membrane	IEA	cellular component
GO:0036038	MKS complex	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0007224	smoothened signaling pathway	IEA	biological process
GO:0060271	cilium assembly	IEA	biological process
GO:0035869	ciliary transition zone	IEA	cellular component
GO:0060170	ciliary membrane	IEA	cellular component
GO:0060271	cilium assembly	ISS	biological process
GO:0035869	ciliary transition zone	ISS	cellular component
GO:0060170	ciliary membrane	ISS	cellular component
GO:0036038	MKS complex	ISS	cellular component
GO:0007224	smoothened signaling pathway	ISS	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881