Male Infertility Database

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Gene id

200150

Gene Summary Protein Summary Gene ontology Diseases PubMed

Gene Summary

Gene Symbol

PLD5 Gene UCSC Ensembl

Aliases

PLDC

Gene name

phospholipase D family member 5

Alternate names

inactive phospholipase D5, inactive PLD 5, inactive choline phosphatase 5, inactive phosphatidylcholine-hydrolyzing phospholipase D5,

Gene location

1q43 (242530545: 242082985) Exons: 20 NC_000001.11

OMIM

614449

Protein Summary

Protein general information

Q8N7P1

Name: Inactive phospholipase D5 (Inactive PLD 5) (Inactive choline phosphatase 5) (Inactive phosphatidylcholine hydrolyzing phospholipase D5) (PLDc)

Length: 536 Mass: 61312

Sequence

MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALV
CCFAILVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIV
SSHWDLNHTHPSACQGQRLFEKLLQLTSQNIEIKLVSDVTADSKVLEALKLKGAEVTYMNMTAYNKGRLQSSFWI
VDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQ
LNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRS
VRVRLLLSFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAY
IGNFDWVGNDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSSLFKLKPLSNKTAT
DDTGGKDPRNV

Structural information

Protein Domains	(215..24-) 1 (/note="PLD-phosphodiesterase) (434..46-) 2" (/note="PLD-phosphodiesterase)
Interpro:	IPR032803 IPR001736
STRING:	ENSP00000440896

Other Databases

GeneCards: PLD5 Malacards: PLD5

Gene ontology

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GO accession	Term name	Evidence code	Go category
GO:0003824	catalytic activity	IEA	molecular function
GO:0016021	integral component of mem brane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

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Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

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PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes	Abstract
21674046	Aberrant C pGs in Low Motility Sperm			18	Male infertility	GSE26881	Show abstract
28606200	Cryptorchi dism			Monozgotic twin s (1 control, I cwith cryptorc hidism)	Male infertility	MeDIP-Seq	Show abstract

Male Infertility knowledgebase

A repository with genes crucial for male fertility

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Diseases

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PubMed references

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Male Infertility knowledgebase

A repository with genes crucial for male fertility

Search Result

Gene Summary

Protein Summary

Gene ontology

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Diseases Expand All | Collapse All

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PubMed references

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Diseases

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