|
Gene id |
1994 |
| Gene Summary Protein Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
ELAVL1 Gene UCSC Ensembl |
|
Aliases |
ELAV1, HUR, Hua, MelG |
|
Gene name |
ELAV like RNA binding protein 1 |
|
Alternate names |
ELAV-like protein 1, ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R), Hu antigen R, embryonic lethal, abnormal vision, drosophila, homolog-like 1, hu-antigen R, |
|
Gene location |
19p13.2 (8005640: 7958572) Exons: 7 NC_000019.10
|
|
Gene summary(Entrez) |
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mR
|
|
OMIM |
603466 |
Protein Summary
|
|
| Pathway id | Pathway name |
|---|
| hsa04152 | AMPK signaling pathway | | hsa04657 | IL-17 signaling pathway | |
|
| Associated diseases |
References |
| Ectopic endometriosis | INFBASE: 20889954 |
| Spermatogenesis defects | MIK: 28445960 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Cryptorchidism | MIK: 28606200 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 21737689 |
Involvemen
t during s
permatogen
esis
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
|