• Gene id: 196394

Gene Summary

• Gene Symbol: AMN1   Gene   UCSC   Ensembl
• Gene name: antagonist of mitotic exit network 1 homolog
• Alternate names: protein AMN1 homolog,
• Gene location: 12p11.21 (31729173: 31671136)     Exons: 12     NC_000012.12
• OMIM: 618650

Protein Summary

• Protein general information: Q8IY45  
  • Name: Protein AMN1 homolog
  • Length: 258  
  • Mass: 28408
• Sequence:

  MPRPRRVSQLLDLCLWCFMKNISRYLTDIKPLPPNIKDRLIKIMSMQGQITDSNISEILHPEVQTLDLRSCDISD
  AALLHLSNCRKLKKLNLNASKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGG
  CLSITDVSLHALGKNCPFLQCVDFSATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRIL
  LFHGCPLITDHSREVLEQLVGPNKLKQVTWTVY

• Structural information:
  • Interpro: IPR001611  IPR006553  IPR032675  
  • STRING: ENSP00000281471
• Other Databases: GeneCards:  AMN1  Malacards:  AMN1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0019005	SCF ubiquitin ligase complex	IBA	cellular component
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IBA	biological process
GO:0006511	ubiquitin-dependent protein catabolic process	IBA	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)