• Gene id: 196264

Gene Summary

• Gene Symbol: MPZL3   Gene   UCSC   Ensembl
• Gene name: myelin protein zero like 3
• Alternate names: myelin protein zero-like protein 3,
• Gene location: 11q23.3 (118252364: 118226689)     Exons: 8     NC_000011.10
• OMIM: 107776

Protein Summary

• Protein general information: Q6UWV2  
  • Name: Myelin protein zero like protein 3
  • Length: 235  
  • Mass: 25989
• Sequence:

  MQQRGAAGSRGCALFPLLGVLFFQGVYIVFSLEIRADAHVRGYVGEKIKLKCTFKSTSDVTDKLTIDWTYRPPSS
  SHTVSIFHYQSFQYPTTAGTFRDRISWVGNVYKGDASISISNPTIKDNGTFSCAVKNPPDVHHNIPMTELTVTER
  GFGTMLSSVALLSILVFVPSAVVVALLLVRMGRKAAGLKKRSRSGYKKSSIEVSDDTDQEEEEACMARLCVRCAE
  CLDSDYEETY

• Structural information:
  • Protein Domains: (32..14-)
    (/note="Ig-like-V-type")
  • Interpro: IPR007110  IPR036179  IPR013783  IPR003599  IPR013106   IPR029862  IPR000920  
  • Prosite: PS50835
  • STRING: ENSP00000278949
• Other Databases: GeneCards:  MPZL3  Malacards:  MPZL3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016020	membrane	IEA	cellular component
GO:0007155	cell adhesion	IEA	biological process
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0042633	hair cycle	IEA	biological process
GO:0030198	extracellular matrix organization	IEA	biological process
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Hypospermatogenesis	MIK: 28361989

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28361989	Hypospermatogenesis			6 (3 controls, 3 Klienfelter syndrome	Male infertility	Microarray