• Gene id: 1667

Gene Summary

• Gene Symbol: DEFA1   Gene   UCSC   Ensembl
• Aliases: DEF1, DEFA2, HNP-1, HP-1, HP1, MRS
• Gene name: defensin alpha 1
• Alternate names: neutrophil defensin 1, defensin, alpha 1, myeloid-related sequence, defensin, alpha 2, myeloid-related sequence,
• Gene location: 8p23.1 (6980119: 6977648)     Exons: 4     NC_000008.11
• Gene summary(Entrez): Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract,
• OMIM: 607433

Protein Summary

Gene ontology

GO accession	Term name	Evidence code	Go category

KEGG pathways

Pathway id	Pathway name
hsa04621	NOD-like receptor signaling pathway
hsa05150	Staphylococcus aureus infection

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881