|
Gene id |
164684 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
WBP2NL Gene UCSC Ensembl |
|
Aliases |
GRAMD7, PAWP |
|
Gene name |
WBP2 N-terminal like |
|
Alternate names |
postacrosomal sheath WW domain-binding protein, WW domain-binding protein 2-like, |
|
Gene location |
22q13.2 (41995102: 42059401) Exons: 10 NC_000022.11
|
|
Gene summary(Entrez) |
WBP2NL is a sperm-specific WW domain-binding protein that promotes meiotic resumption and pronuclear development during oocyte fertilization (Wu et al., 2007 [PubMed 17289678]).[supplied by OMIM, Mar 2008]
|
|
OMIM |
610981 |
|
| Associated diseases |
References |
| Spermatogenesis defects | MIK: 24381051 |
| Sperm-borne oocyte activating defects | MIK: 29397567 |
| Male factor infertility | MIK: 29397567 |
| Fertilizing defects | MIK: 29397567 |
| Role in spermatogenesis | MIK: 24381051 |
| Sperm-borne oocyte activating defects | MIK: 29397567 |
| Fertilization failure | MIK: 29397567 |
| Male infertility | MIK: 29397567 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 29397567 |
Sperm-born
e oocyte a
ctivating
defects, f
ertilizati
on failure
, male inf
ertility
|
|
|
30 (15 fertile
men (control gr
oup) and 15 pat
ients with prev
ious fertilizat
ion failure fol
lowing ICSI (FF
group))
|
Male infertility |
WBP2NL
PLCG1
|
Show abstract |
| 24381051 |
Role in sp
ermatogene
sis
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
|