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Gene id 1613
Gene Summary    Protein Summary    Gene ontology    KEGG pathways    Diseases    PubMed    

Gene Summary

Gene Symbol DAPK3   Gene   UCSC   Ensembl
Aliases DLK, ZIP, ZIPK
Gene name death associated protein kinase 3
Alternate names death-associated protein kinase 3, DAP kinase 3, DAP-like kinase, MYPT1 kinase, ZIP-kinase, zipper-interacting protein kinase,
Gene location 19p13.3 (3971098: 3958452)     Exons: 9     NC_000015.10
Gene summary(Entrez) Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis. [provided by RefSeq, Jul 2008]
OMIM 603289

Protein Summary

Gene ontology

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GO accessionTerm nameEvidence codeGo category

KEGG pathways

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Pathway idPathway name
hsa04140Autophagy - animal
hsa05200Pathways in cancer
hsa05219Bladder cancer
hsa05200Pathways in cancer
hsa04140Autophagy - animal
hsa05219Bladder cancer
Associated diseases References
Plays a crucial role in speramtogenesis MIK: 15910542
Aberrant CpGs in Low Motility Sperm MIK: 21674046
Cryptorchidism MIK: 28606200
Hypospermatogenesis MIK: 28361989
Plays a crucial role in speramtogenesis MIK: 15910542
Unexplained infertility MIK: 25753583

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
15910542 Plays a cr
ucial role
in speram
togenesis


Male infertility
Show abstract
21674046 Aberrant C
pGs in Low
Motility
Sperm

18
Male infertility GSE26881
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract
28361989 Hyposperma
togenesis

6 (3 controls,
3 Klienfelter s
yndrome
Male infertility Microarray
Show abstract
25753583 Unexplaine
d infertil
ity

46 (17 fertile
men, 29 male pa
tients)
Male infertility Microarray
Show abstract