• Gene id: 151903

Gene Summary

• Gene Symbol: CCDC12   Gene   UCSC   Ensembl
• Gene name: coiled-coil domain containing 12
• Alternate names: coiled-coil domain-containing protein 12,
• Gene location: 3p21.31 (46982082: 46916309)     Exons: 10     NC_000003.12
• OMIM: 0

Protein Summary

• Protein general information: Q8WUD4  
  • Name: Coiled coil domain containing protein 12
  • Length: 166  
  • Mass: 19181
• Sequence:

  MEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVP
  QAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSL
  ASAVDAATEQKTCDSD

• Structural information:
  • STRING: ENSP00000292314
• Other Databases: GeneCards:  CCDC12  Malacards:  CCDC12

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005684	U2-type spliceosomal complex	IBA	cellular component
GO:0071014	post-mRNA release spliceosomal complex	IBA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

KEGG pathways

Pathway id	Pathway name
hsa03040	Spliceosome

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq