• Gene id: 151871

Gene Summary

• Gene Symbol: DPPA2   Gene   UCSC   Ensembl
• Aliases: CT100, ECAT15-2, PESCRG1
• Gene name: developmental pluripotency associated 2
• Alternate names: developmental pluripotency-associated protein 2, cancer/testis antigen 100, embryonic stem cell (ESC) associated transcript 15-2, pluripotent embryonic stem cell-related gene 1 protein,
• Gene location: 3q13.13 (109316588: 109293787)     Exons: 11     NC_000003.12
• OMIM: 165250

Protein Summary

• Protein general information: Q7Z7J5  
  • Name: Developmental pluripotency associated protein 2 (Pluripotent embryonic stem cell related gene 1 protein)
  • Length: 298  
  • Mass: 33784
  • Tissue specificity: Expressed in embryonic stem cells. No expression is seen in 5 months embryo, mesenchymal stem cells, embryonic fibrocytes and adult tissues. {ECO
• Sequence:

  MSDANLDSSKKNFLEGEVDDEESVILTLVPVKDDANMEQMEPSVSSTSDVKLEKPKKYNPGHLLQTNEQFTAPQK
  ARCKIPALPLPTILPPINKVCRDTLRDWCQQLGLSTNGKKIEVYLRLHRHAYPEQRQDMPEMSQETRLQRCSRKR
  KAVTKRARLQRSYEMNERAEETNTVEVITSAPGAMLASWARIAARAVQPKALNSCSIPVSVEAFLMQASGVRWCV
  VHGRLLSADTKGWVRLQFHAGQAWVPTTHRRMISLFLLPACIFPSPGIEDNMLCPDCAKRNKKMMKRLMTVEK

• Structural information:
  • Protein Domains: (92..12-)
    (/note="SAP-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00186"-)
  • Interpro: IPR039835  IPR039590  IPR025891  IPR025892  IPR003034  
  • Prosite: PS50800
  • STRING: ENSP00000417710
• Other Databases: GeneCards:  DPPA2  Malacards:  DPPA2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0003682	chromatin binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005654	nucleoplasm	IDA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881