• Gene id: 151354

Gene Summary

• Gene Symbol: LRATD1   Gene   UCSC   Ensembl
• Aliases: FAM84A, NSE1, PP11517
• Gene name: LRAT domain containing 1
• Alternate names: protein LRATD1, family with sequence similarity 84 member A, neurologic sensory protein 1, neurological/sensory 1, protein FAM84A,
• Gene location: 2p24.3 (14632716: 14651915)     Exons: 6     NC_000002.12
• OMIM: 611234

Protein Summary

• Protein general information: Q96KN4  
  • Name: Protein LRATD1 (LRAT domain containing 1) (Neurologic sensory protein 1) (NSE1) (Protein FAM84A)
  • Length: 292  
  • Mass: 32491
  • Tissue specificity: Only detected in testis. Highly expressed in colon cancer cells. {ECO
• Sequence:

  MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDDEEDLDERGQPDKFGVKAPPGCTPCPESPSRHHHHL
  LHQLVLNETQFSAFRGQECIFSKVSGGPQGADLSVYAVTALPALCEPGDLLELLWLQPAPEPPAPAPHWAVYVGG
  GQIIHLHQGEIRQDSLYEAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKRE
  FKAGGEVPAGTQPPQQQYYLKVHLGENKVHTARFHSLEDLIREKRRIDASGRLRVLQELADLVDDKE

• Structural information:
  • Interpro: IPR007053  
  • STRING: ENSP00000295092
• Other Databases: GeneCards:  LRATD1  Malacards:  LRATD1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0048870	cell motility	IMP	biological process
GO:0000902	cell morphogenesis	IMP	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)