Gene id |
151242 |
Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
Gene Symbol |
PPP1R1C Gene UCSC Ensembl |
Aliases |
IPP5 |
Gene name |
protein phosphatase 1 regulatory inhibitor subunit 1C |
Alternate names |
protein phosphatase 1 regulatory subunit 1C, PP1 inhibitor protein 5, inhibitor-5 of protein phosphatase 1, protein phosphatase 1 regulatory subunit 1A, |
Gene location |
2q31.3-q32.1 (181954240: 182131384) Exons: 9 NC_000002.12
|
Gene summary(Entrez) |
Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or
|
OMIM |
613240 |
Protein Summary
|
Protein general information
| Q8WVI7
Name: Protein phosphatase 1 regulatory subunit 1C (Inhibitor 5 of protein phosphatase 1) (IPP5)
Length: 109 Mass: 12346
|
Sequence |
MEPNSPKKIQFAVPVFQSQIAPEAAEQIRKRRPTPASLVILNEHNPPEIDDKRGPNTQGELQNASPKQRKQSVYT PPTIKGVKHLKGQNESAFPEEEEGTNEREEQRDH
|
Structural information |
|
Other Databases |
GeneCards: PPP1R1C  Malacards: PPP1R1C |
|
GO accession | Term name | Evidence code | Go category |
---|
GO:0035556 |
intracellular signal tran sduction
|
IBA |
biological process |
GO:0005737 |
cytoplasm
|
IBA |
cellular component |
GO:0004864 |
protein phosphatase inhib itor activity
|
IEA |
molecular function |
GO:0007165 |
signal transduction
|
IEA |
biological process |
GO:0004864 |
protein phosphatase inhib itor activity
|
IEA |
molecular function |
GO:0051301 |
cell division
|
IEA |
biological process |
GO:0005737 |
cytoplasm
|
IEA |
cellular component |
GO:0007049 |
cell cycle
|
IEA |
biological process |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005737 |
cytoplasm
|
IEA |
cellular component |
GO:0032515 |
negative regulation of ph osphoprotein phosphatase activity
|
IEA |
biological process |
GO:0032515 |
negative regulation of ph osphoprotein phosphatase activity
|
IEA |
biological process |
|
|
Associated diseases |
References |
Teratozoospermia | MIK: 17327269 |
|
|
PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
17327269 |
Teratozoos permia
|
|
|
19 (6 controls , 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
|