• Gene id: 151188

Gene Summary

• Gene Symbol: ARL6IP6   Gene   UCSC   Ensembl
• Aliases: AIP-6, AIP6, PFAAP1
• Gene name: ADP ribosylation factor like GTPase 6 interacting protein 6
• Alternate names: ADP-ribosylation factor-like protein 6-interacting protein 6, ADP-ribosylation factor GTPase 6 interacting protein 6, ADP-ribosylation factor-like 6 interacting protein 6, ADP-ribosylation-like factor 6 interacting protein 6, ARL-6-interacting protein 6, phosp,
• Gene location: 2q23.3 (152717647: 152762395)     Exons: 11     NC_000002.12
• OMIM: 616495

Protein Summary

• Protein general information: Q8N6S5  
  • Name: ADP ribosylation factor like protein 6 interacting protein 6 (ARL 6 interacting protein 6) (Aip 6) (Phosphonoformate immuno associated protein 1)
  • Length: 226  
  • Mass: 24676
• Sequence:

  MSFAESGWRSALRRRGPGTPGPVARPSYSSFTQGDSWGEGEVDEEEGCDQVARDLRAEFSAGAWSEPRKRSVLPP
  DGNGSPVLPDKRNGIFPAAAGSRAQPRRWPVQVLSILCSLLFAILLAFLLAIAYLIVKELHAENLKNEDDVDTGL
  LGFWTLLIISLTAGFSCCSFSWTVTYFDSFEPGMFPPTPLSPARFKKLTGHSFHMGYSMAILNGIVAALTVAWCL
  M

• Structural information:
  • Interpro: IPR029383  
  • STRING: ENSP00000315357
• Other Databases: GeneCards:  ARL6IP6  Malacards:  ARL6IP6

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016020	membrane	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005637	nuclear inner membrane	IEA	cellular component
GO:0005637	nuclear inner membrane	IEA	cellular component
GO:0005637	nuclear inner membrane	ISS	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881