• Gene id: 150160

Gene Summary

• Gene Symbol: CCT8L2   Gene   UCSC   Ensembl
• Aliases: CESK1
• Gene name: chaperonin containing TCP1 subunit 8 like 2
• Alternate names: T-complex protein 1 subunit theta-like 2, chaperonin containing TCP1, subunit 8 (theta)-like 2, putative T-complex protein 1 subunit theta-like 2,
• Gene location: 22q11.1 (16592809: 16590750)     Exons: 1     NC_000022.11

Protein Summary

• Protein general information: Q96SF2  
  • Name: T complex protein 1 subunit theta like 2
  • Length: 557  
  • Mass: 59388
• Sequence:

  MDSTVPSALELPQRLALNPRESPRSPEEEEPHLLSSLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATA
  ILRALELEHPAAWLLREAGQTQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSL
  AIQSLGPLEDPSWALHSVMNTHTLSPMDHLTKLVAHACWAIKELDGSFKPERVGVCALPGGTLEDSCLLPGLAIS
  GKLCGQMATVLSGARVALFACPFGPAHPNAPATARLSSPADLAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVD
  EETLTLADKYGIVVIQARSWMEIIYLSEVLDTPLLPRLLPPQRPGKCQRVYRQELGDGLAVVFEWECTGTPALTV
  VLRGATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSGPAFLAFAWALKYLPK
  TLAENAGLAVSDVMAEMSGVHQGGNLLMGVGTEGIINVAQEGVWDTLIVKAQGFRAVAEVVLQLVTVDEIVVAKK
  SPTHQEIWNPDSKKTKKHPPPVETKKILGLNN

• Structural information:
  • Interpro: IPR017998  IPR002423  IPR027409  IPR027413  IPR027410  
  • STRING: ENSP00000353048
• Other Databases: GeneCards:  CCT8L2  Malacards:  CCT8L2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005832	chaperonin-containing T-complex	IBA	cellular component
GO:0005524	ATP binding	IEA	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0000166	nucleotide binding	IEA	molecular function
GO:0005524	ATP binding	IEA	molecular function
GO:0015269	calcium-activated potassium channel activity	TAS	molecular function
GO:0005253	anion channel activity	TAS	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0071805	potassium ion transmembrane transport	IEA	biological process
GO:0015698	inorganic anion transport	IEA	biological process

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray