• Gene id: 149420

Gene Summary

• Gene Symbol: PDIK1L   Gene   UCSC   Ensembl
• Aliases: CLIK1L, STK35L2
• Gene name: PDLIM1 interacting kinase 1 like
• Alternate names: serine/threonine-protein kinase PDIK1L, casein kinase,
• Gene location: 1p36.11 (26109130: 26125554)     Exons: 5     NC_000001.11
• OMIM: 610785

Protein Summary

• Protein general information: Q8N165  
  • Name: Serine/threonine protein kinase PDIK1L (EC 2.7.11.1) (PDLIM1 interacting kinase 1 like)
  • Length: 341  
  • Mass: 38546
  • Tissue specificity: Expressed in liver, kidney, pancreas, spleen, thymus and prostate. {ECO
• Sequence:

  MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSIKSQHPNVIHLEECIL
  QKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSS
  ALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYM
  APEVWEGHYTAKADIFALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
  NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET

• Structural information:
  • Protein Domains: (8..33-)
    (/note="Protein-kinase)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00159"-)
  • Interpro: IPR011009  IPR000719  IPR017441  IPR008271  
  • Prosite: PS00107 PS50011 PS00108
  • STRING: ENSP00000363389
• Other Databases: GeneCards:  PDIK1L  Malacards:  PDIK1L

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0004672	protein kinase activity	IBA	molecular function
GO:0004672	protein kinase activity	IEA	molecular function
GO:0005524	ATP binding	IEA	molecular function
GO:0006468	protein phosphorylation	IEA	biological process
GO:0016740	transferase activity	IEA	molecular function
GO:0016301	kinase activity	IEA	molecular function
GO:0004674	protein serine/threonine kinase activity	IEA	molecular function
GO:0016310	phosphorylation	IEA	biological process
GO:0005524	ATP binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0000166	nucleotide binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005654	nucleoplasm	IDA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)