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Gene id 148327
Gene Summary    KEGG pathways    Diseases    PubMed    

Gene Summary
Gene Symbol CREB3L4   Gene   UCSC   Ensembl
Aliases AIBZIP, ATCE1, CREB3, CREB4, JAL, hJAL
Gene name cAMP responsive element binding protein 3 like 4
Alternate names cyclic AMP-responsive element-binding protein 3-like protein 4, CREB-4, androgen-induced basic leucine zipper protein, attaching to CRE-like 1, cAMP responsive element binding protein 1, cAMP-responsive element-binding protein 3-like protein 4, cAMP-responsive ,
Gene location 1q21.3 (153967486: 153974363)     Exons: 13     NC_000001.11
Gene summary(Entrez) This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in
OMIM 607138

KEGG pathways

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Pathway idPathway name
hsa04668TNF signaling pathway
hsa04024cAMP signaling pathway
hsa04022cGMP-PKG signaling pathway
hsa04151PI3K-Akt signaling pathway
hsa04152AMPK signaling pathway
hsa04911Insulin secretion
hsa04922Glucagon signaling pathway
hsa04915Estrogen signaling pathway
hsa04926Relaxin signaling pathway
hsa04918Thyroid hormone synthesis
hsa04928Parathyroid hormone synthesis, secretion and action
hsa04916Melanogenesis
hsa04925Aldosterone synthesis and secretion
hsa04927Cortisol synthesis and secretion
hsa04261Adrenergic signaling in cardiomyocytes
hsa04962Vasopressin-regulated water reabsorption
hsa04725Cholinergic synapse
hsa04728Dopaminergic synapse
hsa04211Longevity regulating pathway
hsa04714Thermogenesis
hsa05203Viral carcinogenesis
hsa05215Prostate cancer
hsa05016Huntington disease
hsa05030Cocaine addiction
hsa05031Amphetamine addiction
hsa05034Alcoholism
hsa04931Insulin resistance
hsa04934Cushing syndrome
hsa05166Human T-cell leukemia virus 1 infection
hsa05161Hepatitis B
hsa05163Human cytomegalovirus infection
hsa05165Human papillomavirus infection
hsa04151PI3K-Akt signaling pathway
hsa04915Estrogen signaling pathway
hsa05166Human T-cell leukemia virus 1 infection
hsa04928Parathyroid hormone synthesis, secretion and action
hsa04728Dopaminergic synapse
hsa04714Thermogenesis
hsa04261Adrenergic signaling in cardiomyocytes
hsa04022cGMP-PKG signaling pathway
hsa05203Viral carcinogenesis
hsa04024cAMP signaling pathway
hsa05163Human cytomegalovirus infection
hsa04911Insulin secretion
hsa04725Cholinergic synapse
hsa04152AMPK signaling pathway
hsa04925Aldosterone synthesis and secretion
hsa05165Human papillomavirus infection
hsa04935Growth hormone synthesis, secretion and action
hsa04211Longevity regulating pathway
hsa05031Amphetamine addiction
hsa04931Insulin resistance
hsa04918Thyroid hormone synthesis
hsa05034Alcoholism
hsa05016Huntington disease
hsa04916Melanogenesis
hsa04926Relaxin signaling pathway
hsa04922Glucagon signaling pathway
hsa05161Hepatitis B
hsa04962Vasopressin-regulated water reabsorption
hsa04934Cushing syndrome
hsa05215Prostate cancer
hsa04927Cortisol synthesis and secretion
hsa05030Cocaine addiction
hsa04668TNF signaling pathway

Diseases

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Associated diseases References
Play a role in male germ cell development MIK: 16107712
Play a role in male germ cell development MIK: 16107712
Teratozoospermia MIK: 17327269

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
16107712 Play a rol
e in male
germ cell
developmen
t

Male infertility
Show abstract
17327269 Teratozoos
permia
13 (5 controls,
8 cases)
 Male infertility GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
 Show abstract