• Gene id: 147991

Gene Summary

• Gene Symbol: DPY19L3   Gene   UCSC   Ensembl
• Gene name: dpy-19 like C-mannosyltransferase 3
• Alternate names: probable C-mannosyltransferase DPY19L3, dpy-19 like 3, dpy-19-like 3, dpy-19-like protein 3, protein dpy-19 homolog 3,
• Gene location: 19q13.11 (32405764: 32485889)     Exons: 21     NC_000019.10
• OMIM: 613894

Protein Summary

• Protein general information: Q6ZPD9  
  • Name: Probable C mannosyltransferase DPY19L3 (EC 2.4.1. ) (Dpy 19 like protein 3) (Protein dpy 19 homolog 3)
  • Length: 716  
  • Mass: 83197
  • Tissue specificity: Widely expressed. {ECO
• Sequence:

  MMSIRQRREIRATEVSEDFPAQEENVKLENKLPSGCTSRRLWKILSLTIGGTIALCIGLLTSVYLATLHENDLWF
  SNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFHGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVLPIQ
  KYLEPVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIA
  AITYFLRPNLQPLSERLTLLAIFISTFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLV
  CILQFFNSMILGSLLISFNLSVFIARKLQKNLKTGSFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKSDEHIF
  KFLKAKFGLGATRDFDANLYLCEEAFGLLPFNTFGRLSDTLLFYAYIFVLSITVIVAFVVAFHNLSDSTNQQSVG
  KMEKGTVDLKPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFGLCSPEIWELLLKSVHLYNPKRICIMRY
  SVPILILLYLCYKFWPGMMDELSELREFYDPDTVELMNWINSNTPRKAVFAGSMQLLAGVKLCTGRTLTNHPHYE
  DSSLRERTRAVYQIYAKRAPEEVHALLRSFGTDYVILEDSICYERRHRRGCRLRDLLDIANGHMMDGPGENDPDL
  KPADHPRFCEEIKRNLPPYVAYFTRVFQNKTFHVYKLSRNK

• Structural information:
  • Interpro: IPR018732  IPR030039  
  • STRING: ENSP00000344937
• Other Databases: GeneCards:  DPY19L3  Malacards:  DPY19L3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0000030	mannosyltransferase activity	IBA	molecular function
GO:0005637	nuclear inner membrane	IBA	cellular component
GO:0018406	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	IBA	biological process
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016740	transferase activity	IEA	molecular function
GO:0016757	transferase activity, transferring glycosyl groups	IEA	molecular function
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)