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Gene id 145497
Gene Summary    Protein Summary    Diseases    PubMed    

Gene Summary

Gene Symbol LRRC74A   Gene   UCSC   Ensembl
Aliases C14orf166B, LRRC74
Gene name leucine rich repeat containing 74A
Alternate names leucine-rich repeat-containing protein 74A, leucine rich repeat containing 74, leucine-rich repeat-containing protein 74,
Gene location 14q24.3 (76826384: 76870303)     Exons: 18     NC_000014.9
OMIM 0

Protein Summary

Protein general information Q0VAA2  

Name: Leucine rich repeat containing protein 74A (Leucine rich repeat containing protein 74)

Length: 488  Mass: 54535

Sequence MHIQFPSKPTLPRACWEGRITAGSPGMPPDEIEIEPVRQSSDKMLYCEAESPPTVEKVKPARENSETDLEIEDDE
KFFTTGQKELYLEACKLMGVVPVSYFIRNMEESYVNLNHHGLGPRGTKAIAIALVSNMAVTKLELEDNCIMEEGV
LSLVEMLQENYYLQEMNISNNHLGLEGARIISDFFERNSSSIWSLELSGNDFKEDSAALLCQALSTNYQIKKLDL
SHNQFSDVGGEHLGQMLAINVGLTSLDLSWNNFHTRGAVALCNGLRGNVTLTKLDLSMNGFGNEVALALGEVLRL
NRCLVYLDIGGNDIGNEGASKISKGLESNESLRVLKLFLNPINMDGAILLILAIKRNPKSRMEELDISNVLVSEQ
FMKTLDGVYAVHPQLDVVFKAVQGLSPKKTIFLLTNPMKLIQSYADQHKITIVDFFKSLNPTGTMKMSVDEFQKV
MIEQNKVPLNQYQVREVIKKLDEKTGMVNFSFLNTMKP
Structural information
Interpro:  IPR001611  IPR032675  
MINT:  
STRING:   ENSP00000377369
Other Databases GeneCards:  LRRC74A  Malacards:  LRRC74A
Associated diseases References
Cryptorchidism MIK: 28606200
Teratozoospermia MIK: 17327269

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
17327269 Teratozoos
permia

19 (6 controls
, 13 cases)
Male infertility GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract