• Gene id: 140701

Gene Summary

• Gene Symbol: ABHD16B   Gene   UCSC   Ensembl
• Aliases: C20orf135, dJ591C20.1
• Gene name: abhydrolase domain containing 16B
• Alternate names: protein ABHD16B, abhydrolase domain-containing protein 16B, alpha/beta hydrolase domain-containing protein 16B,
• Gene location: 20q13.33 (63861497: 63862987)     Exons: 7     NC_000020.11

Protein Summary

• Protein general information: Q9H3Z7  
  • Name: Protein ABHD16B (EC 3. . . ) (Alpha/beta hydrolase domain containing protein 16B) (Abhydrolase domain containing protein 16B)
  • Length: 469  
  • Mass: 52555
• Sequence:

  MCVICFVKALVRVFKIYLTASYTYPFRGWPVAFRWDDVRAVGRSSSHRALTCAAAAAGVWLLRDETLGGDALGRP
  PRGARSQAQCLLQQLRELPGQLASYALAHSLGRWLVYPGSVSLMTRALLPLLQQGQERLVERYHGRRAKLVACDG
  NEIDTMFMDRRQHPGSHVHGPRLVICCEGNAGFYEMGCLSAPLEAGYSVLGWNHPGFGSSTGVPFPQHDANAMDV
  VVEYALHRLHFPPAHLVVYGWSVGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPHSWKGLVVRTVREHFN
  LNVAEQLCCYPGPVLLLRRTQDDVVSTSGRLRPLSPGDVEGNRGNELLLRLLEHRYPVVMAREGRAVVTRWLRAG
  SLAQEAAFYARYRVDEDWCLALLRSYRARCEEELEGEEALGPHGPAFPWLVGQGLSSRRRRRLALFLARKHLKNV
  EATHFSPLEPEEFQLPWRL

• Structural information:
  • Protein Domains: (174..29-)
    (/note="AB-hydrolase-1)
    (/evidence="ECO:0000255"-)
  • Interpro: IPR029058  IPR000073  
  • STRING: ENSP00000358932
• Other Databases: GeneCards:  ABHD16B  Malacards:  ABHD16B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0006660	phosphatidylserine catabolic process	IBA	biological process
GO:0047372	acylglycerol lipase activity	IBA	molecular function
GO:0004620	phospholipase activity	IBA	molecular function
GO:0052651	monoacylglycerol catabolic process	IBA	biological process
GO:0016787	hydrolase activity	IEA	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Hypospermatogenesis	MIK: 28361989
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28361989	Hypospermatogenesis			6 (3 controls, 3 Klienfelter syndrome	Male infertility	Microarray