• Gene id: 140576

Gene Summary

• Gene Symbol: S100A16   Gene   UCSC   Ensembl
• Aliases: AAG13, DT1P1A7, S100F
• Gene name: S100 calcium binding protein A16
• Alternate names: protein S100-A16, aging-associated gene 13 protein, aging-associated protein 13, protein S100-F,
• Gene location: 1q21.3 (153613136: 153606882)     Exons: 4     NC_000001.11
• OMIM: 617437

Protein Summary

• Protein general information: Q96FQ6  
  • Name: Protein S100 A16 (Aging associated gene 13 protein) (Protein S100 F) (S100 calcium binding protein A16)
  • Length: 103  
  • Mass: 11801
  • Tissue specificity: Ubiquitous (PubMed
• Sequence:

  MSDCYTELEKAVIVLVENFYKYVSKYSLVKNKISKSSFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRIS
  FDEYWTLIGGITGPIAKLIHEQEQQSSS

• Structural information:
  • Protein Domains: (12..4-)
    (/note="EF-hand-)
    (-)
    (/evidence="ECO:0000305|PubMed:14684152-)
    (54..8-)
    (/note="EF-hand-2)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00448"-)
  • Interpro: IPR011992  IPR018247  IPR002048  IPR001751  IPR013787  
  • Prosite: PS00018 PS50222 PS00303
  • PDB: 2L50 2L51 3NXA
  • PDBsum: 2L50 2L51 3NXA
  • STRING: ENSP00000357693
• Other Databases: GeneCards:  S100A16  Malacards:  S100A16

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005829	cytosol	IDA	cellular component
GO:0005730	nucleolus	IDA	cellular component
GO:0005509	calcium ion binding	IDA	molecular function
GO:0042803	protein homodimerization activity	IPI	molecular function
GO:0005509	calcium ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005730	nucleolus	IDA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005509	calcium ion binding	IEA	molecular function
GO:0051592	response to calcium ion	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0042802	identical protein binding	IEA	molecular function
GO:0005730	nucleolus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005886	plasma membrane	IDA	cellular component
GO:0005829	cytosol	IDA	cellular component
GO:0005615	extracellular space	IDA	cellular component
GO:0003723	RNA binding	HDA	molecular function
GO:0070062	extracellular exosome	HDA	cellular component
GO:0070062	extracellular exosome	HDA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)