• Gene id: 138255

Gene Summary

• Gene Symbol: C9orf135   Gene   UCSC   Ensembl
• Gene name: chromosome 9 open reading frame 135
• Alternate names: protein C9orf135, uncharacterized protein C9orf135,
• Gene location: 9q21.12 (185425984: 185399536)     Exons: 12     NC_000004.12

Protein Summary

• Protein general information: Q5VTT2  
  • Name: Protein C9orf135
  • Length: 229  
  • Mass: 26445
  • Tissue specificity: Expressed in undifferentiated embryonic stem cells. {ECO
• Sequence:

  MDSLDRSCQDWCDRKQHWLEIGPPDLVERKGSLTLRSHHKKYSKPVLVYSWHRDREAFPKGYDIEGPEKVKKLCN
  STYRRLGTDESPIWTSETHEKLSQMCLNTEWVEMKSKALLNEETVSSGIIERVTGLPATGFGAVFPRHPPDWSKM
  CALTTYSEDYVPPYDYQPHAYPCQDDYSIVHRKCRSQFTDLNGSKRFGINTWHDESGIYANSDVKQKLYPLTSGP
  IVPI

• Structural information:
  • Interpro: IPR027905  
  • STRING: ENSP00000366402
• Other Databases: GeneCards:  C9orf135  Malacards:  C9orf135

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005886	plasma membrane	IBA	cellular component
GO:0005737	cytoplasm	IDA	cellular component
GO:0005886	plasma membrane	IDA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005886	plasma membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005886	plasma membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray