• Gene id: 134492

Gene Summary

• Gene Symbol: NUDCD2   Gene   UCSC   Ensembl
• Aliases: NudCL2
• Gene name: NudC domain containing 2
• Alternate names: nudC domain-containing protein 2, NudC-like protein 2,
• Gene location: 5q34 (163460101: 163446525)     Exons: 4     NC_000005.10

Protein Summary

• Protein general information: Q8WVJ2  
  • Name: NudC domain containing protein 2
  • Length: 157  
  • Mass: 17676
• Sequence:

  MSAPFEERSGVVPCGTPWGQWYQTLEEVFIEVQVPPGTRAQDIQCGLQSRHVALSVGGREILKGKLFDSTIADEG
  TWTLEDRKMVRIVLTKTKRDAANCWTSLLESEYAADPWVQDQMQRKLTLERFQKENPGFDFSGAEISGNYTKGGP
  DFSNLEK

• Structural information:
  • Protein Domains: (14..10-)
    (/note="CS-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00547"-)
  • Interpro: IPR007052  IPR008978  IPR037898  IPR037902  
  • Prosite: PS51203
  • CDD: cd06494
  • DIP: 59509
  • STRING: ENSP00000304854
• Other Databases: GeneCards:  NUDCD2  Malacards:  NUDCD2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0006457	protein folding	IBA	biological process
GO:0032502	developmental process	IBA	biological process
GO:0051082	unfolded protein binding	IBA	molecular function
GO:0005737	cytoplasm	IBA	cellular component
GO:0000776	kinetochore	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0000775	chromosome, centromeric region	IEA	cellular component
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005694	chromosome	IEA	cellular component
GO:0005622	intracellular	IDA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0000922	spindle pole	IEA	cellular component
GO:0000777	condensed chromosome kinetochore	IEA	cellular component
GO:0005815	microtubule organizing center	IEA	cellular component
GO:0045171	intercellular bridge	IDA	cellular component
GO:0072686	mitotic spindle	IDA	cellular component
GO:0005829	cytosol	IDA	cellular component
GO:0015630	microtubule cytoskeleton	IDA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881