• Gene id: 134288

Gene Summary

• Gene Symbol: TMEM174   Gene   UCSC   Ensembl
• Gene name: transmembrane protein 174
• Alternate names: transmembrane protein 174,
• Gene location: 5q13.2 (102846031: 102875994)     Exons: 15     NC_000013.11
• OMIM: 614909

Protein Summary

• Protein general information: Q8WUU8  
  • Name: Transmembrane protein 174
  • Length: 243  
  • Mass: 26287
  • Tissue specificity: Predominantly expressed in kidney. {ECO
• Sequence:

  MEQGSGRLEDFPVNVFSVTPYTPSTADIQVSDDDKAGATLLFSGIFLGLVGITFTVMGWIKYQGVSHFEWTQLLG
  PVLLSVGVTFILIAVCKFKMLSCQLCKESEERVPDSEQTPGGPSFVFTGINQPITFHGATVVQYIPPPYGSPEPM
  GINTSYLQSVVSPCGLITSGGAAAAMSSPPQYYTIYPQDNSAFVVDEGCLSFTDGGNHRPNPDVDQLEETQLEEE
  ACACFSPPPYEEIYSLPR

• Structural information:
  • Interpro: IPR027835  
  • STRING: ENSP00000296776
• Other Databases: GeneCards:  TMEM174  Malacards:  TMEM174

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005783	endoplasmic reticulum	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005789	endoplasmic reticulum membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)