• Gene id: 134111

Gene Summary

• Gene Symbol: UBE2QL1   Gene   UCSC   Ensembl
• Gene name: ubiquitin conjugating enzyme E2 Q family like 1
• Alternate names: ubiquitin-conjugating enzyme E2Q-like protein 1, E2Q-like ubiquitin-conjugating enzyme 1, ubiquitin-conjugating enzyme E2Q family-like 1,
• Gene location: 5p15.31 (6437346: 6496722)     Exons: 3     NC_000005.10
• OMIM: 123995

Protein Summary

• Protein general information: A1L167  
  • Name: Ubiquitin conjugating enzyme E2Q like protein 1 (EC 2.3.2.23) (E2Q like ubiquitin conjugating enzyme 1)
  • Length: 161  
  • Mass: 18338
• Sequence:

  MKELQDIARLSDRFISVELVDESLFDWNVKLHQVDKDSVLWQDMKETNTEFILLNLTFPDNFPFSPPFMRVLSPR
  LENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAASLVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHEK
  YGWVTPPVSDG

• Structural information:
  • Interpro: IPR000608  IPR016135  
  • Prosite: PS50127
  • STRING: ENSP00000382713
• Other Databases: GeneCards:  UBE2QL1  Malacards:  UBE2QL1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0061631	ubiquitin conjugating enzyme activity	IBA	molecular function
GO:0005634	nucleus	IBA	cellular component
GO:0000209	protein polyubiquitination	IBA	biological process
GO:0005634	nucleus	IDA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0016740	transferase activity	IEA	molecular function
GO:0000166	nucleotide binding	IEA	molecular function
GO:0005524	ATP binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0061631	ubiquitin conjugating enzyme activity	IEA	molecular function
GO:0061631	ubiquitin conjugating enzyme activity	IDA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005886	plasma membrane	IDA	cellular component
GO:0005654	nucleoplasm	IDA	cellular component
GO:0016567	protein ubiquitination	IEA	biological process

KEGG pathways

Pathway id	Pathway name
hsa04120	Ubiquitin mediated proteolysis

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq