• Gene id: 133688

Gene Summary

• Gene Symbol: UGT3A1   Gene   UCSC   Ensembl
• Gene name: UDP glycosyltransferase family 3 member A1
• Alternate names: UDP-glucuronosyltransferase 3A1, UDP glycosyltransferase 3 family, polypeptide A1, UDPGT 3A1,
• Gene location: 5p13.2 (36001054: 35951005)     Exons: 10     NC_000005.10
• OMIM: 617202

Protein Summary

• Protein general information: Q6NUS8  
  • Name: UDP glucuronosyltransferase 3A1 (UDPGT 3A1) (EC 2.4.1.17)
  • Length: 523  
  • Mass: 59151
• Sequence:

  MVGQRVLLLVAFLLSGVLLSEAAKILTISTLGGSHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEEEKSYQ
  VIRWFSPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQCSYLLSRKDIMDSLKNENYDLVFVEAFDFC
  SFLIAEKLVKPFVAILPTTFGSLDFGLPSPLSYVPVFPSLLTDHMDFWGRVKNFLMFFSFSRSQWDMQSTFDNTI
  KEHFPEGSRPVLSHLLLKAELWFVNSDFAFDFARPLLPNTVYIGGLMEKPIKPVPQDLDNFIANFGDAGFVLVAF
  GSMLNTHQSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHGGQNSV
  MEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMKQVIEDKRYKSAVVAASVILHSQPLS
  PAQRLVGWIDHILQTGGATHLKPYAFQQPWHEQYLIDVFVFLLGLTLGTMWLCGKLLGVVARWLRGARKVKKT

• Structural information:
  • Interpro: IPR002213  IPR035595  
  • Prosite: PS00375
  • STRING: ENSP00000274278
• Other Databases: GeneCards:  UGT3A1  Malacards:  UGT3A1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0043231	intracellular membrane-bounded organelle	IBA	cellular component
GO:0008194	UDP-glycosyltransferase activity	IBA	molecular function
GO:0008194	UDP-glycosyltransferase activity	IEA	molecular function
GO:0016740	transferase activity	IEA	molecular function
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016757	transferase activity, transferring glycosyl groups	IEA	molecular function
GO:0015020	glucuronosyltransferase activity	IEA	molecular function
GO:0015020	glucuronosyltransferase activity	IDA	molecular function
GO:0043541	UDP-N-acetylglucosamine transferase complex	IDA	cellular component
GO:0008194	UDP-glycosyltransferase activity	IDA	molecular function
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray