• Gene id: 132671

Gene Summary

• Gene Symbol: SPATA18   Gene   UCSC   Ensembl
• Aliases: Mieap, SPETEX1
• Gene name: spermatogenesis associated 18
• Alternate names: mitochondria-eating protein, spermatogenesis associated 18 homolog, testis tissue sperm-binding protein Li 71n,
• Gene location: 4q12 (52051303: 52097304)     Exons: 14     NC_000003.12
• Gene summary(Entrez): This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality con
• OMIM: 612814

Diseases

Associated diseases	References
Spermatogenesis defects	MIK: 15236321
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Non obstructive azoospermia	MIK: 24012201
Sertoli cell only syndrome	MIK: 23869807
Role in spermatogenesis especially in cell differentiation from late elongate spermatids to mature spermatozoa	MIK: 15236321
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
15236321	Role in spermatogenesis especially in cell differentiation from late elongate spermatids to mature spermatozoa				Male infertility
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
23869807	Non obstructive azoospermia, Sertoli cell only syndrome			20 (4 controls, 16 cases)	Male infertility	GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881