• Gene id: 129787

Gene Summary

• Gene Symbol: TMEM18   Gene   UCSC   Ensembl
• Aliases: lncND
• Gene name: transmembrane protein 18
• Alternate names: transmembrane protein 18,
• Gene location: 2p25.3 (677405: 663876)     Exons: 7     NC_000002.12
• OMIM: 613220

Protein Summary

• Protein general information: Q96B42  
  • Name: Transmembrane protein 18
  • Length: 140  
  • Mass: 16265
• Sequence:

  MPSAFSVSSFPVSIPAVLTQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQIGHFLCLVILVYCAEYINEAAAM
  NWRLFSKYQYFDSRGMFISIVFSAPLLVNAMIIVVMWVWKTLNVMTDLKNAQERRKEKKRRRKED

• Structural information:
  • Interpro: IPR026721  
  • STRING: ENSP00000281017
• Other Databases: GeneCards:  TMEM18  Malacards:  TMEM18

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016477	cell migration	IDA	biological process
GO:0031965	nuclear membrane	IDA	cellular component
GO:0003677	DNA binding	IEA	molecular function
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0031965	nuclear membrane	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq