• Gene id: 128077

Gene Summary

• Gene Symbol: LIX1L   Gene   UCSC   Ensembl
• Gene name: limb and CNS expressed 1 like
• Alternate names: LIX1-like protein, Lix1 homolog-like,
• Gene location: 1q21.1 (145958037: 145933422)     Exons: 6     NC_000001.11

Protein Summary

• Protein general information: Q8IVB5  
  • Name: LIX1 like protein
  • Length: 337  
  • Mass: 36563
• Sequence:

  METMRAQRLQPGVGTSGRGTLRALRPGVTGAAAATATPPAGPPPAPPPPAPPPPPLLLSGAPGLPLPPGAAGSPA
  VLREAVEAVVRSFAKHTQGYGRVNVVEALQEFWQMKQSRGADLKNGALVVYEMVPSNSPPYVCYVTLPGGSCFGS
  FQFCPTKAEARRSAAKIALMNSVFNEHPSRRITDEFIEKSVSEALASFNGNREEADNPNTGIGAFRFMLESNKGK
  SMLEFQELMTVFQLLHWNGSLKAMRERQCSRQEVLAHYSHRALDDDIRHQMALDWVSREQSVPGALSRELASTER
  ELDEARLAGKELRFHKEKKDILVLAAGQLGNMHSSNC

• Structural information:
  • Interpro: IPR029270  
  • STRING: ENSP00000474487
• Other Databases: GeneCards:  LIX1L  Malacards:  LIX1L

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0008150	biological_process	ND	biological process
GO:0005575	cellular_component	ND	cellular component
GO:0003674	molecular_function	ND	molecular function
GO:0097352	autophagosome maturation	IBA	biological process
GO:0006914	autophagy	IBA	biological process
GO:0005737	cytoplasm	IBA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881