• Gene id: 126308

Gene Summary

• Gene Symbol: MOB3A   Gene   UCSC   Ensembl
• Aliases: MOB-LAK, MOB1C, MOBKL2A, moblak
• Gene name: MOB kinase activator 3A
• Alternate names: MOB kinase activator 3A, MOB LAK, MOB1, Mps One Binder kinase activator-like 2A, mob1 homolog 2A, mps one binder kinase activator-like 2A,
• Gene location: 19p13.3 (66070271: 66244743)     Exons: 27     NC_000011.10

Protein Summary

• Protein general information: Q96BX8  
  • Name: MOB kinase activator 3A (MOB LAK) (Mob1 homolog 2A) (Mps one binder kinase activator like 2A)
  • Length: 217  
  • Mass: 25464
• Sequence:

  MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLI
  YGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQ
  TVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH

• Structural information:
  • Interpro: IPR005301  IPR036703  
  • STRING: ENSP00000349575
• Other Databases: GeneCards:  MOB3A  Malacards:  MOB3A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0046872	metal ion binding	IEA	molecular function
GO:0005622	intracellular	IDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray