• Gene id: 126248

Gene Summary

• Gene Symbol: WDR88   Gene   UCSC   Ensembl
• Aliases: PQWD
• Gene name: WD repeat domain 88
• Alternate names: WD repeat-containing protein 88, PQQ repeat and WD repeat domain containing, PQQ repeat and WD repeat-containing protein,
• Gene location: 19q13.11 (65792292: 65655233)     Exons: 34     NC_000015.10

Protein Summary

• Protein general information: Q6ZMY6  
  • Name: WD repeat containing protein 88 (PQQ repeat and WD repeat containing protein)
  • Length: 472  
  • Mass: 52621
• Sequence:

  MASPPRCSPTAHDRECKLPPPSAPASEYCPGKLSWGTMARALGRFKLSIPHTHLLATLDPLALDREPPPHLLPEK
  HQVPEKLIWGDQDPLSKIPFKILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVE
  CSITGDSSRVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAENITTVSVI
  KDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIW
  NVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAISNNK
  KWILSASKDRTMRLWNIEEIDEIPLVIKYKKAVGLKLKQCERCDRPFSIFKSDTSSEMFTQCVFCRIDTRGLPAD
  TSSSSSSSERENSPPPRGSKDD

• Structural information:
  • Interpro: IPR020472  IPR018391  IPR002372  IPR011047  IPR015943   IPR001680  IPR019775  IPR017986  
  • Prosite: PS00678 PS50082 PS50294
  • STRING: ENSP00000348129
• Other Databases: GeneCards:  WDR88  Malacards:  WDR88

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq