• Gene id: 126147

Gene Summary

• Gene Symbol: NTN5   Gene   UCSC   Ensembl
• Gene name: netrin 5
• Alternate names: netrin-5, netrin-1-like protein,
• Gene location: 19q13.33 (48673118: 48661406)     Exons: 9     NC_000019.10

Protein Summary

• Protein general information: Q8WTR8  
  • Name: Netrin 5 (Netrin 1 like protein)
  • Length: 489  
  • Mass: 53174
• Sequence:

  MPVTFALLLLLGQATADPCYDPQGRPQFCLPPVTQLAAVAASCPQACALSPGNHLGARETCNGSLTLALGGPFLL
  TSVSLRFCTPGPPALILSAAWASGGPWRLLWHRPAWPGALGGPERVTFHSTPGPKATVAASHLRVEFGGQAGLAA
  AGLRGRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNS
  ELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGV
  TGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSLRRYCQQDHVLRAQVL
  ASEAAGPAWQRLAVRVLAVYKQRAQPVRRGDQDAWVPRADLTCGCLRLQPGTDYLLLGSAVGDPDPTRLILDRHG
  LALPWRPRWARPLKRLQQEERAGGCRGVRAPTPSPRPEH

• Structural information:
  • Protein Domains: (157..21-)
    1 (/note="Laminin-EGF-like)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00460-)
    (212..27-)
    2 (/note="Laminin-EGF-like)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00460-)
    (275..32-)
    3 (/note="Laminin-EGF-like)
    (/evidence="ECO-)
  • Interpro: IPR002049  IPR001134  IPR018933  IPR008993  
  • Prosite: PS00022 PS01248 PS50027 PS50189
  • STRING: ENSP00000270235
• Other Databases: GeneCards:  NTN5  Malacards:  NTN5

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016358	dendrite development	IBA	biological process
GO:0009887	animal organ morphogenesis	IBA	biological process
GO:0005604	basement membrane	IBA	cellular component
GO:0009888	tissue development	IBA	biological process
GO:0008045	motor neuron axon guidance	IBA	biological process
GO:0022008	neurogenesis	ISS	biological process
GO:0005576	extracellular region	IEA	cellular component
GO:0007275	multicellular organism development	IEA	biological process
GO:0007399	nervous system development	IEA	biological process
GO:0022008	neurogenesis	IEA	biological process
GO:0005576	extracellular region	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq