• Gene id: 126074

Gene Summary

• Gene Symbol: SWSAP1   Gene   UCSC   Ensembl
• Aliases: C19orf39, SWS1AP1, ZSWIM7AP1
• Gene name: SWIM-type zinc finger 7 associated protein 1
• Alternate names: ATPase SWSAP1, SWS1-associated protein 1, ZSWIM7-associated protein 1, zinc finger, SWIM-type containing 7 associated protein 1,
• Gene location: 19p13.2 (11374665: 11376168)     Exons: 2     NC_000019.10
• OMIM: 614536

Protein Summary

• Protein general information: Q6NVH7  
  • Name: ATPase SWSAP1 (SWIM type zinc finger 7 associated protein 1) (SWS1 associated protein 1) (ZSWIM7 associated protein 1) (ZSWIM7AP1)
  • Length: 229  
  • Mass: 24311
• Sequence:

  MPAAGPPLLLLGTPGSGKTALLFAAALEAAGEGQGPVLFLTRRPLQSMPRGTGTTLDPMRLQKIRFQYPPSTREL
  FRLLCSAHEAPGPAPSLLLLDGLEEYLAEDPEPQEAAYLIALLLDTAAHFSHRLGPGRDCGLMVALQTQEEAGSG
  DVLHLALLQRYFPAQCWLQPDAPGPGEHGLRACLEPGGLGPRTEWWVTFRSDGEMMIAPWPTQAGDPSSGKGSSS
  GGQP

• Structural information:
  • Interpro: IPR027417  
  • STRING: ENSP00000310008
• Other Databases: GeneCards:  SWSAP1  Malacards:  SWSAP1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0097196	Shu complex	IBA	cellular component
GO:0016887	ATPase activity	IBA	molecular function
GO:0003697	single-stranded DNA binding	IBA	molecular function
GO:0000724	double-strand break repair via homologous recombination	IBA	biological process
GO:0097196	Shu complex	IDA	cellular component
GO:0016887	ATPase activity	IDA	molecular function
GO:0003697	single-stranded DNA binding	IDA	molecular function
GO:0050821	protein stabilization	IMP	biological process
GO:0000724	double-strand break repair via homologous recombination	IMP	biological process
GO:0006281	DNA repair	IEA	biological process
GO:0006974	cellular response to DNA damage stimulus	IEA	biological process
GO:0006310	DNA recombination	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0003677	DNA binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881