• Gene id: 124491

Gene Summary

• Gene Symbol: TMEM170A   Gene   UCSC   Ensembl
• Aliases: TMEM170
• Gene name: transmembrane protein 170A
• Alternate names: transmembrane protein 170A, transmembrane protein 170,
• Gene location: 16q23.1 (75464756: 75443053)     Exons: 6     NC_000016.10
• OMIM: 0

Protein Summary

• Protein general information: Q8WVE7  
  • Name: Transmembrane protein 170A
  • Length: 144  
  • Mass: 15250
• Sequence:

  MEREGSGGSGGSAGLLQQILSLKVVPRVGNGTLCPNSTSLCSFPEMWYGVFLWALVSSLFFHVPAGLLALFTLRH
  HKYGRFMSVSILLMGIVGPITAGILTSAAIAGVYRAAGKEMIPFEALTLGTGQTFCVLVVSFLRILATL

• Structural information:
  • Interpro: IPR019334  
  • STRING: ENSP00000454404
• Other Databases: GeneCards:  TMEM170A  Malacards:  TMEM170A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005789	endoplasmic reticulum membrane	IDA	cellular component
GO:0005635	nuclear envelope	IDA	cellular component
GO:0051292	nuclear pore complex assembly	IMP	biological process
GO:0006998	nuclear envelope organization	IMP	biological process
GO:0071786	endoplasmic reticulum tubular network organization	IMP	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005783	endoplasmic reticulum	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005789	endoplasmic reticulum membrane	IEA	cellular component
GO:0005635	nuclear envelope	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881