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Gene id 124222
Gene Summary    Protein Summary    Gene ontology    Diseases    PubMed    

Gene Summary

Gene Symbol PAQR4   Gene   UCSC   Ensembl
Gene name progestin and adipoQ receptor family member 4
Alternate names progestin and adipoQ receptor family member 4, progestin and adipoQ receptor family member IV,
Gene location 16p13.3 (2969347: 2973483)     Exons: 4     NC_000016.10
OMIM 185260

Protein Summary

Protein general information Q8N4S7  

Name: Progestin and adipoQ receptor family member 4 (Progestin and adipoQ receptor family member IV)

Length: 273  Mass: 29126

Tissue specificity: Relatively widely expressed in a range of tissues. {ECO

Sequence MAFLAGPRLLDWASSPPHLQFNKFVLTGYRPASSGSGCLRSLFYLHNELGNIYTHGLALLGFLVLVPMTMPWGQL
GKDGWLGGTHCVACLAPPAGSVLYHLFMCHQGGSAVYARLLALDMCGVCLVNTLGALPIIHCTLACRPWLRPAAL
VGYTVLSGVAGWRALTAPSTSARLRAFGWQAAARLLVFGARGVGLGSGAPGSLPCYLRMDALALLGGLVNVARLP
ERWGPGRFDYWGNSHQIMHLLSVGSILQLHAGVVPDLLWAAHHACPRD
Structural information
Interpro:  IPR004254  
STRING:   ENSP00000321804
Other Databases GeneCards:  PAQR4  Malacards:  PAQR4

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0038023 signaling receptor activi
ty
IBA molecular function
GO:0016021 integral component of mem
brane
IEA cellular component
GO:0016021 integral component of mem
brane
IEA cellular component
GO:0016020 membrane
IEA cellular component
GO:0016020 membrane
IEA cellular component
Associated diseases References
Aberrant CpGs in Low Motility Sperm MIK: 21674046
Cryptorchidism MIK: 28606200
Male factor infertility MIK: 29961538

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
21674046 Aberrant C
pGs in Low
Motility
Sperm

18
Male infertility GSE26881
Show abstract
29961538 Male facto
r infertil
ity

318 (128 couple
s presenting wi
th OAT (MF) and
118 maternal a
ge-matched cont
rol (no MF) sub
jects undergoin
g infertility t
reatment, 72 su
rplus cryoprese
rved blastocyst
s)
Male infertility RNA-seq
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract