• Gene id: 124220

Gene Summary

• Gene Symbol: ZG16B   Gene   UCSC   Ensembl
• Aliases: EECP, HRPE773, JCLN2, PAUF, PRO1567
• Gene name: zymogen granule protein 16B
• Alternate names: zymogen granule protein 16 homolog B, endocrine and exocrine protein, jacalin-like lectin domain containing 2, pancreatic adenocarcinoma upregulated factor,
• Gene location: 16p13.3 (2830171: 2832283)     Exons: 4     NC_000016.10
• OMIM: 0

Protein Summary

• Protein general information: Q96DA0  
  • Name: Zymogen granule protein 16 homolog B
  • Length: 208  
  • Mass: 22739
• Sequence:

  MGAQGAQESIKAMWRVPGTTRRPVTGESPGMHRPEAMLLLLTLALLGGPTWAGKMYGPGGGKYFSTTEDYDHEIT
  GLRVSVGLLLVKSVQVKLGDSWDVKLGALGGNTQEVTLQPGEYITKVFVAFQAFLRGMVMYTSKDRYFYFGKLDG
  QISSAYPSQEGQVLVGIYGQYQLLGIKSIGFEWNYPLEEPTTEPPVNLTYSANSPVGR

• Structural information:
  • Protein Domains: (53..18-)
    (/note="Jacalin-type-lectin)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU01088"-)
  • Interpro: IPR001229  IPR036404  
  • Prosite: PS51752
  • PDB: 3AQG
  • PDBsum: 3AQG
  • STRING: ENSP00000371715
• Other Databases: GeneCards:  ZG16B  Malacards:  ZG16B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005615	extracellular space	IBA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0030246	carbohydrate binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005576	extracellular region	IEA	cellular component
GO:0001895	retina homeostasis	HEP	biological process
GO:0070062	extracellular exosome	HDA	cellular component
GO:0070062	extracellular exosome	HDA	cellular component
GO:0005615	extracellular space	HDA	cellular component
GO:0005615	extracellular space	HDA	cellular component
GO:0005615	extracellular space	HDA	cellular component
GO:0070062	extracellular exosome	HDA	cellular component
GO:0003674	molecular_function	ND	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq