• Gene id: 122830

Gene Summary

• Gene Symbol: NAA30   Gene   UCSC   Ensembl
• Aliases: C14orf35, MAK3, Mak3p, NAT12, NAT12P
• Gene name: N-alpha-acetyltransferase 30, NatC catalytic subunit
• Alternate names: N-alpha-acetyltransferase 30, N-acetyltransferase 12 (GCN5-related, putative), N-acetyltransferase MAK3 homolog, natC catalytic subunit, putative N-acetyltransferase,
• Gene location: 14q22.3 (57390585: 57415905)     Exons: 39     NC_000014.9
• OMIM: 617989

Protein Summary

• Protein general information: Q147X3  
  • Name: N alpha acetyltransferase 30 (EC 2.3.1.256) (N acetyltransferase 12) (N acetyltransferase MAK3 homolog) (NatC catalytic subunit)
  • Length: 362  
  • Mass: 39320
• Sequence:

  MAEVPPGPSSLLPPPAPPAPAAVEPRCPFPAGAALACCSEDEEDDEEHEGGGSRSPAGGESATVAAKGHPCLRCP
  QPPQEQQQLNGLISPELRHLRAAASLKSKVLSVAEVAATTATPDGGPRATATKGAGVHSGERPPHSLSSNARTAV
  PSPVEAAAASDPAAARNGLAEGTEQEEEEEDEQVRLLSSSLTADCSLRSPSGREVEPGEDRTIRYVRYESELQMP
  DIMRLITKDLSEPYSIYTYRYFIHNWPQLCFLAMVGEECVGAIVCKLDMHKKMFRRGYIAMLAVDSKYRRNGIGT
  NLVKKAIYAMVEGDCDEVVLETEITNKSALKLYENLGFVRDKRLFRYYLNGVDALRLKLWLR

• Structural information:
  • Protein Domains: (214..36-)
    (/note="N-acetyltransferase-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00532"-)
  • Interpro: IPR016181  IPR000182  
  • Prosite: PS51186
  • STRING: ENSP00000452521
• Other Databases: GeneCards:  NAA30  Malacards:  NAA30

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0031417	NatC complex	IBA	cellular component
GO:0004596	peptide alpha-N-acetyltransferase activity	IBA	molecular function
GO:0017196	N-terminal peptidyl-methionine acetylation	IBA	biological process
GO:0031417	NatC complex	IDA	cellular component
GO:0004596	peptide alpha-N-acetyltransferase activity	IDA	molecular function
GO:0005844	polysome	IDA	colocalizes with
GO:0005737	cytoplasm	IDA	cellular component
GO:0005634	nucleus	IDA	cellular component
GO:0005737	cytoplasm	IDA	cellular component
GO:0008080	N-acetyltransferase activity	IEA	molecular function
GO:0016740	transferase activity	IEA	molecular function
GO:0016746	transferase activity, transferring acyl groups	IEA	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0017196	N-terminal peptidyl-methionine acetylation	IDA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005829	cytosol	IDA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)