|
Gene id |
121504 |
| Gene Summary Protein Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
HIST4H4 Gene UCSC Ensembl |
|
Aliases |
H4/p |
|
Gene name |
histone cluster 4 H4 |
|
Alternate names |
histone H4, histone 4, H4, |
|
Gene location |
12p12.3 (14771130: 14770719) Exons: 1 NC_000012.12
|
|
Gene summary(Entrez) |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core hi
|
|
OMIM |
615069 |
Protein Summary
|
|
|
|
|
| Associated diseases |
References |
| Testicular mixed atrophy | MIK: 18001726 |
| Spermatogenesis defects | MIK: 18001726 |
| Hypospermatogenesis | MIK: 28361989 |
| Testicular mixed atrophy | MIK: 18001726 |
| Impaired spermatogenesis | MIK: 18001726 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 18001726 |
Testicular
mixed atr
ophy, impa
ired sperm
atogenesis
|
|
|
23 azoospermic
men
|
Male infertility |
Hypac
|
Show abstract |
| 28361989 |
Hyposperma
togenesis
|
|
|
6 (3 controls,
3 Klienfelter s
yndrome
|
Male infertility |
Microarray
|
Show abstract |
|