• Gene id: 114571

Gene Summary

• Gene Symbol: SLC22A9   Gene   UCSC   Ensembl
• Aliases: HOAT4, OAT4, OAT7, UST3H, ust3
• Gene name: solute carrier family 22 member 9
• Alternate names: solute carrier family 22 member 9, organic anion transporter 4, organic anion transporter 7, solute carrier family 22 (organic anion transporter), member 9, solute carrier family 22 (organic anion/cation transporter), member 9,
• Gene location: 11q12.3 (70452173: 70459904)     Exons: 2     NC_000014.9
• OMIM: 607579

Protein Summary

• Protein general information: Q8IVM8  
  • Name: Solute carrier family 22 member 9 (Organic anion transporter 7)
  • Length: 553  
  • Mass: 62169
  • Tissue specificity: Specifically expressed in liver by hepatocytes (at protein level). {ECO
• Sequence:

  MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTGALSQDALLRI
  SIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRISFSSTIVTEWDLVCDSQSLTSVAKF
  VFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWA
  THRFQAMGITLGMCPSGIAFMTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELR
  KAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLHVQHL
  GNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAICLLAIIFVPQEMQTLREVLATLGLGASALAN
  TLAFAHGNEVIPTIIRARAMGINATFANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLF
  DTIQDEKNERKDPREPKQEDPRVEVTQF

• Structural information:
  • Interpro: IPR011701  IPR020846  IPR036259  
  • Prosite: PS50850
  • STRING: ENSP00000279178
• Other Databases: GeneCards:  SLC22A9  Malacards:  SLC22A9

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0015711	organic anion transport	IBA	biological process
GO:0009914	hormone transport	IDA	biological process
GO:0015913	short-chain fatty acid import	IDA	biological process
GO:0015636	short-chain fatty acid transmembrane transporter activity	IDA	molecular function
GO:0015301	anion:anion antiporter activity	IDA	molecular function
GO:0015347	sodium-independent organic anion transmembrane transporter activity	IDA	molecular function
GO:0016323	basolateral plasma membrane	IDA	cellular component
GO:0043252	sodium-independent organic anion transport	IDA	biological process
GO:0022857	transmembrane transporter activity	IEA	molecular function
GO:0055085	transmembrane transport	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0005886	plasma membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016323	basolateral plasma membrane	IEA	cellular component
GO:0098656	anion transmembrane transport	IEA	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)