|
Gene id |
1139 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
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|
Gene Symbol |
CHRNA7 Gene UCSC Ensembl |
|
Aliases |
CHRNA7-2, NACHRA7 |
|
Gene name |
cholinergic receptor nicotinic alpha 7 subunit |
|
Alternate names |
neuronal acetylcholine receptor subunit alpha-7, a7 nicotinic acetylcholine receptor, alpha 7 neuronal nicotinic acetylcholine receptor, alpha-7 nicotinic cholinergic receptor subunit, cholinergic receptor, nicotinic alpha 7, cholinergic receptor, nicotinic, a, |
|
Gene location |
15q13.3 (32030461: 32173017) Exons: 13 NC_000015.10
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|
Gene summary(Entrez) |
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structu
|
|
OMIM |
118511 |
Protein Summary
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|
| GO accession | Term name | Evidence code | Go category |
|---|
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| Associated diseases |
References |
| Chromosome 15q13.3 microdeletion syndrome | KEGG:H01877 |
| Chromosome 15q13.3 microdeletion syndrome | KEGG:H01877 |
| Alzheimer's disease | PMID:15465084 |
| Lewy body dementia | PMID:15465084 |
| Schizophrenia | PMID:9012828 |
| Cryptorchidism | MIK: 28606200 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|