• Gene id: 113174

Gene Summary

• Gene Symbol: SAAL1   Gene   UCSC   Ensembl
• Aliases: SPACIA1
• Gene name: serum amyloid A like 1
• Alternate names: protein SAAL1, synoviocyte proliferation-associated in collagen-induced arthritis 1, synoviocyte proliferation-associated in collagen-induced arthritis protein 1,
• Gene location: 11p15.1 (18106081: 18080291)     Exons: 12     NC_000011.10

Protein Summary

• Protein general information: Q96ER3  
  • Name: Protein SAAL1 (Synoviocyte proliferation associated in collagen induced arthritis protein 1) (SPACIA1)
  • Length: 474  
  • Mass: 53558
  • Tissue specificity: Highly expressed in testis and ovary, and to a lesser extent in the lung, spleen and the heart (at protein level). {ECO
• Sequence:

  MDRNPSPPPPGRDKEEEEEVAGGDCIGSTVYSKHWLFGVLSGLIQIVSPENTKSSSDDEEQLTELDEEMENEICR
  VWDMSMDEDVALFLQEFNAPDIFMGVLAKSKCPRLREICVGILGNMACFQEICVSISSDKNLGQVLLHCLYDSDP
  PTLLETSRLLLTCLSQAEVASVWVERIQEHPAIYDSICFIMSSSTNVDLLVKVGEVVDKLFDLDEKLMLEWVRNG
  AAQPLDQPQEESEEQPVFRLVPCILEAAKQVRSENPEWLDVYMHILQLLTTVDDGIQAIVHCPDTGKDIWNLLFD
  LVCHEFCQSDDPPIILQEQKTVLASVFSVLSAIYASQTEQEYLKIEKVDLPLIDSLIRVLQNMEQCQKKPENSAE
  SNTEETKRTDLTQDDFHLKILKDILCEFLSNIFQALTKETVAQGVKEGQLSKQKCSSAFQNLLPFYSPVVEDFIK
  ILREVDKALADDLEKNFPSLKVQT

• Structural information:
  • Interpro: IPR016024  
  • STRING: ENSP00000432487
• Other Databases: GeneCards:  SAAL1  Malacards:  SAAL1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005615	extracellular space	IBA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)