|
Gene id |
11191 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
PTENP1 Gene UCSC Ensembl |
|
Aliases |
PTEN-rs, PTEN2, PTENpg1, PTH2, psiPTEN |
|
Gene name |
phosphatase and tensin homolog pseudogene 1 |
|
Alternate names |
PTEN/MMAC1 pseudogene, phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1, phosphatase and tensin homolog pseudogene 1 (functional), |
|
Gene location |
9p13.3 (33677419: 33673503) Exons: 2 NC_000009.12
|
|
Gene summary(Entrez) |
The phosphatase and tensin homolog (PTEN) gene encodes a tumor suppressor that functions by negatively regulating the AKT/PKB signaling pathway. A highly homologous processed pseudogene of PTEN is found on chromosome 9 and regulates PTEN by both sense and
|
|
OMIM |
613531 |
|
| Associated diseases |
References |
| Hypospermatogenesis | MIK: 28361989 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28361989 |
Hyposperma
togenesis
|
|
|
6 (3 controls,
3 Klienfelter s
yndrome
|
Male infertility |
Microarray
|
Show abstract |
|