• Gene id: 10969

Gene Summary

• Gene Symbol: EBNA1BP2   Gene   UCSC   Ensembl
• Aliases: EBP2, NOBP, P40
• Gene name: EBNA1 binding protein 2
• Alternate names: probable rRNA-processing protein EBP2, nuclear FGF3 binding protein, nucleolar protein p40, nucleolar protein p40; homolog of yeast EBNA1-binding protein,
• Gene location: 1p34.2 (43172569: 43164173)     Exons: 9     NC_000001.11
• OMIM: 614443

Protein Summary

• Protein general information: Q99848  
  • Name: Probable rRNA processing protein EBP2 (EBNA1 binding protein 2) (Nucleolar protein p40)
  • Length: 306  
  • Mass: 34852
  • Tissue specificity: Ubiquitous. {ECO
• Sequence:

  MDTPPLSDSESESDESLVTDRELQDAFSRGLLKPGLNVVLEGPKKAVNDVNGLKQCLAEFKRDLEWVERLDVTLG
  PVPEIGGSEAPAPQNKDQKAVDPEDDFQREMSFYRQAQAAVLAVLPRLHQLKVPTKRPTDYFAEMAKSDLQMQKI
  RQKLQTKQAAMERSEKAKQLRALRKYGKKVQTEVLQKRQQEKAHMMNAIKKYQKGFSDKLDFLEGDQKPLAQRKK
  AGAKGQQMRKGPSAKRRYKNQKFGFGGKKKGSKWNTRESYDDVSSFRAKTAHGRGLKRPGKKGSNKRPGKRTREK
  MKNRTH

• Structural information:
  • Interpro: IPR008610  
  • STRING: ENSP00000407323
• Other Databases: GeneCards:  EBNA1BP2  Malacards:  EBNA1BP2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0042273	ribosomal large subunit biogenesis	IBA	biological process
GO:0034399	nuclear periphery	IBA	cellular component
GO:0030687	preribosome, large subunit precursor	IBA	cellular component
GO:0005730	nucleolus	IBA	cellular component
GO:0006364	rRNA processing	IBA	biological process
GO:0005730	nucleolus	IDA	cellular component
GO:0042254	ribosome biogenesis	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005730	nucleolus	IEA	cellular component
GO:0005730	nucleolus	IDA	cellular component
GO:0003723	RNA binding	HDA	molecular function
GO:0003723	RNA binding	HDA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)