|
Gene id |
10941 |
| Gene Summary Protein Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
UGT2A1 Gene UCSC Ensembl |
|
Aliases |
UDPGT2A1 |
|
Gene name |
UDP glucuronosyltransferase family 2 member A1 complex locus |
|
Alternate names |
UDP-glucuronosyltransferase 2A1, UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus, UDP glycosyltransferase 2 family, polypeptide A1, uridine diphosphate glycosyltransferase 2 family, member A1, |
|
Gene location |
4q13.3 (69653246: 69588416) Exons: 9 NC_000004.12
|
|
Gene summary(Entrez) |
The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. Th
|
|
OMIM |
604716 |
Protein Summary
|
|
| Pathway id | Pathway name |
|---|
| hsa01100 | Metabolic pathways | | hsa00983 | Drug metabolism - other enzymes | | hsa05204 | Chemical carcinogenesis | | hsa00980 | Metabolism of xenobiotics by cytochrome P450 | | hsa00982 | Drug metabolism - cytochrome P450 | | hsa00830 | Retinol metabolism | | hsa00140 | Steroid hormone biosynthesis | | hsa00860 | Porphyrin and chlorophyll metabolism | | hsa00040 | Pentose and glucuronate interconversions | | hsa00053 | Ascorbate and aldarate metabolism | |
|
| Associated diseases |
References |
| Cryptorchidism | MIK: 28606200 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|