• Gene id: 10890

Gene Summary

• Gene Symbol: RAB10   Gene   UCSC   Ensembl
• Gene name: RAB10, member RAS oncogene family
• Alternate names: ras-related protein Rab-10, GTP-binding protein RAB10, ras-related GTP-binding protein,
• Gene location: 2p23.3 (26034083: 26137453)     Exons: 7     NC_012920.1
• Gene summary(Entrez): RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009]
• OMIM: 612672

KEGG pathways

Pathway id	Pathway name
hsa00140	Steroid hormone biosynthesis
hsa00590	Arachidonic acid metabolism
hsa04152	AMPK signaling pathway
hsa04144	Endocytosis
hsa04144	Endocytosis
hsa04152	AMPK signaling pathway

Diseases

Associated diseases	References
Involved in mammalian spermiogenesis	MIK: 28067790
Cryptorchidism	MIK: 28606200
Involved in mammalian spermiogenesis	MIK: 28067790
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28067790	Involved in mammalian spermiogenesis				Male infertility
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq