• Gene id: 10772

Gene Summary

• Gene Symbol: SRSF10   Gene   UCSC   Ensembl
• Aliases: FUSIP1, FUSIP2, NSSR, PPP1R149, SFRS13, SFRS13A, SRp38, SRrp40, TASR, TASR1, TASR2
• Gene name: serine and arginine rich splicing factor 10
• Alternate names: serine/arginine-rich splicing factor 10, 40 kDa SR-repressor protein, FUS interacting protein (serine-arginine rich) 1, FUS-interacting protein (serine-arginine rich) 2, SR splicing factor 10, TLS-associated SR protein, TLS-associated protein TASR, TLS-associate,
• Gene location: 1p36.11 (23980462: 23964346)     Exons: 8     NC_000017.11
• Gene summary(Entrez): This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA
• OMIM: 605221

KEGG pathways

Pathway id	Pathway name
hsa03040	Spliceosome

Diseases

Associated diseases	References
Spermatogenesis defects	MIK: 21980524
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Role in sperm maturation and fertilization	MIK: 21980524
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21980524	Role in sperm maturation and fertilization				Male infertility
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881