• Gene id: 10419

Gene Summary

• Gene Symbol: PRMT5   Gene   UCSC   Ensembl
• Aliases: HRMT1L5, HSL7, IBP72, JBP1, SKB1, SKB1Hs
• Gene name: protein arginine methyltransferase 5
• Alternate names: protein arginine N-methyltransferase 5, 72 kDa ICln-binding protein, HMT1 hnRNP methyltransferase-like 5, SKB1 homolog, histone-arginine N-methyltransferase PRMT5, jak-binding protein 1, shk1 kinase-binding protein 1 homolog,
• Gene location: 14q11.2 (22929391: 22920525)     Exons: 18     NC_000004.12
• Gene summary(Entrez): This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor su
• OMIM: 604045

KEGG pathways

Pathway id	Pathway name
hsa03013	RNA transport

Diseases

Associated diseases	References
Required for sperm cell survival	MIK: 26072710
Spermatogenesis defects	MIK: 26072710
Spermatogenesis defects	MIK: 26565999
Involved in spermatogenesis	MIK: 26565999
Required for sperm cell survival	MIK: 26072710
Spermatogenesis defects	MIK: 26072710

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
26565999	Involved in spermatogenesis				Male infertility
26072710	Required for sperm cell survival, spermatogenesis defects				Male infertility