• Gene id: 10207

Gene Summary

• Gene Symbol: PATJ   Gene   UCSC   Ensembl
• Aliases: Cipp, INADL, InaD-like, hINADL
• Gene name: PATJ crumbs cell polarity complex component
• Alternate names: inaD-like protein, PALS1-associated tight junction protein, PDZ domain protein, channel-interacting PDZ domain protein, channel-interacting PDZ domain-containing protein, inactivation no after-potential D-like protein, inactivation-no-afterpotential D-like, prot,
• Gene location: 1p31.3 (61742476: 62163914)     Exons: 52     NC_000001.11
• Gene summary(Entrez): This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to th
• OMIM: 603199

KEGG pathways

Pathway id	Pathway name
hsa05165	Human papillomavirus infection
hsa04530	Tight junction
hsa04390	Hippo signaling pathway

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq