|
Gene id |
10188 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
TNK2 Gene UCSC Ensembl |
|
Aliases |
ACK, ACK-1, ACK1, p21cdc42Hs |
|
Gene name |
tyrosine kinase non receptor 2 |
|
Alternate names |
activated CDC42 kinase 1, activated Cdc42-associated kinase 1, activated p21cdc42Hs kinase, tyrosine kinase non-receptor protein 2, |
|
Gene location |
3q29 (195909008: 195863363) Exons: 26 NC_000006.12
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|
Gene summary(Entrez) |
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-termi
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|
OMIM |
606994 |
|
| Associated diseases |
References |
| Associated with sperm motility, may play a role in capacitation and/or the acrosome reaction | MIK: 9209099 |
| Associated with sperm motility, may play a role in capacitation and/or the acrosome reaction | MIK: 9209099 |
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|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 9209099 |
Associated
with sper
m motility
, may play
a role in
capacitat
ion and/or
the acros
ome reacti
on
|
|
|
|
Male infertility |
|
Show abstract |
|